NFL Football Odds: San Francisco 49ers vs. St. Louis Rams

In terms of the playoffs, this week's game between the San Francisco 49ers and St. Louis Rams has no importance at all. (AP Images)"]

However, that does not mean it is not worth a look when making a few bets.

The Rams have a 4-19 record in division games since the start of the 2005 season, and it is even worse at home. The Rams’ only division win at home since 2005 came over the 49ers in 2006, making them 1-10 in that time frame with San Francisco coming to town.

St. Louis has lost eight in a row after winning its first two under Jim Haslett, including blowing a 10-point halftime lead in a last-second 23-20 loss to the Seahawks in Week 15.

The 5.5-point favored Niners might have to play without their top RB this week. Frank Gore's status is in question after he missed his first game of the season with an ankle sprain.