Week 12 NFL Picks, Predictions & Matchups: Green Bay vs. Detroit

The Packers are first to kickoff on Thanksgiving. (AP Images)

Happy turkey day everyone! Time to bet on some NFL football.

The banged-up Green Bay Packers will rely on a makeshift defense today when they try to continue their dominance over a Detroit Lions team that will likely be without Matthew Stafford, who was injured while leading his team to an exciting comeback win last week.

NFL betting odds have the Packers favored by 11.5 points.

Green Bay is going to have to get accustomed to playing without Al Harris and Aaron Kampman, as both will have season-ending knee surgery. Harris will be replaced by Tramon Williams while seventh-round rookie Brad Jones will likely take Williams’ place.

It would be a big blow for the Lions if Stafford couldn’t play, considering he is coming off the best performance of his young career. Stafford set an NFL rookie passing record with 422 yards Sunday and became the youngest player to throw five touchdowns in a game.

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