Week 15 NFL Picks: Detroit Lions vs. Indianapolis Colts

Will you have your money on the Colts or the Lions? (Images)"]

The Indianapolis Colts look to continue their charge toward a seventh straight playoff berth on Sunday when they host the desperate Detroit Lions, who are running out of chances to avoid becoming the NFL's first 0-16 team.

Since a 31-21 loss at Tennessee on Oct. 27, the Colts have won six in a row (three ATS), compiling the longest active winning streak in the league. Indy has given up just four passing touchdowns all season, on pace to break the 16-game NFL record of nine, while intercepting opponents 14 times.

As heavy 17-point favorites, it will be hard for the Colts to take the Lions seriously but even an off day is good enough to beat Detroit.

The Lions are 1-2 in Indianapolis since the Colts moved there in 1984, including a 30-18 loss in their most recent visit Oct. 29, 2000.